Enrichment#
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Calculate a weighted average gene expression profile for each archetype. |
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Calculate weights for the data points based on their distance to archetypes using a squared exponential kernel. |
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Compute the enrichment of metadata categories across archetypes. |
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Extract top enriched biological processes for each archetype based on significance and enrichment score. |
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Extract the top biological processes that are uniquely enriched in each archetype. |